DermNet NZ


Facts about the skin from DermNet New Zealand Trust. Topic index: A B C D E F G H I J K L M N O P Q R S T U V W X Y Z


What is chloracne?

Chloracne is a rare skin condition caused by certain toxic chemicals, including the dioxins. It develops a few months after swallowing, inhaling or touching the responsible agent.

The name "chloracne" is misleading, because it is not related to acne. Rather than overactive sebaceous glands, as occurs in acne, the glands are destroyed and replaced by epidermal cysts.

Most cases of chloracne are due to occupational exposure but chloracne can also arise after accidental environmental poisoning. One hundred and ninety-three cases of chloracne resulted from an industrial accident in Seveso, Italy in 1976. Deliberate dioxin poisoning is blamed for Ukrainian President Victor Yushchenko's changed appearance in September 2004.

Victor Yushchenko ©TIME
President Victor Yushchenko, December 2004 © TIME South Pacific, with permission

What causes chloracne?

Chloracne is caused by exposure to halogenated aromatic hydrocarbons, which are most often found in:

Chloracne is the most common skin sign of dioxin poisoning. Responsible chemicals include:

What are the features of chloracne?

The features of chloracne are:

Blackheads and cysts
Inflammatory lesions
Chloracne blackheads

The lesions are most often seen on the cheeks, behind the ears, in the armpits and in the groin. Although they resemble acne, the skin is not usually oily; in fact the oil glands are often smaller than usual.

Other skin problems seen in patients with chloracne include:

Other health problems

Other health problems may include:

The data for an association with other health problems and birth defects are conflicting.

What is the treatment for chloracne?

Once chloracne has been recognised, the source of exposure must be identified and the affected individual and other workers must be removed from exposure to it.

Occupational disease due to chemical exposure is a notifiable condition. If you live in New Zealand, contact Worksafe NZ of the Department of Labour, New Zealand for further information.

Most chloracne lesions clear up within 2 years providing exposure to the chemical has stopped. In some cases they persist much longer because the chemical continues to be slowly released from fat cells.

Persistent cases may be helped by standard treatments for acne, particularly oral antibiotics and sometimes isotretinoin. Comedones and cysts can be cauterised.

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Author: Dr Amanda Oakley Dermatologist, Hamilton, New Zealand. Reviewed and updated by Vanessa Ngan, Staff Writer, February 2014, and Clare Morrison, Copy Editor, April 2014.

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If you have any concerns with your skin or its treatment, see a dermatologist for advice.