Mycology of dermatophyte infections
What is mycology?
Mycology is the study of fungi.
What are dermatophyte fungi?
Dermatophyte fungi are the ringworm fungi (tinea). They depend on their host, which may be an animal ("zoophilic") or a human ("anthropophilic") and need to spread from one host to another to survive. Dermatophytes may also prefer to live in the soil ("geophilic").
Anthropophilic dermatophytes are so well adapted to living on human skin that they provoke minimal inflammatory reaction. Zoophilic or geophilic dermatophytes will often provoke a more vigorous inflammatory reaction when they attempt to invade human skin.
There are three genera of dermatophytes, recognised by the nature of their macroconidae (asexual spores):
- Trichophyton (abbreviated as "T")
- Microsporum ("M")
- Epidermophyton ("E")
There are about 40 species. Their spores can live for more than a year in human skin scales in the environment.
Anthropophilic organisms include:
- T. rubrum (most common in New Zealand)
- T. interdigitale
- T. tonsurans (very common in the USA)
- M. audouinii
- T. violaceum
- M. ferrugineum
- T. schoenleinii
- T. megninii
- T. soudanense
- T. yaoundei
Zoophilic organisms include:
- M. canis (originating from cats and dogs)
- T. equinum (originating from horses)
- T. erinacei (originating from hedgehogs and other animals)
- T. verrucosum (originating from cattle)
- M. nanum (originating from pigs)
- M. distortum (a variant of M canis).
Geophilic organisms include:
- M. gypseum
- M. fulvum
How are dermatophyte fungi diagnosed?
Fungal infection may be suspected clinically or with the help of dermoscopy. The presence of a dermatophyte infection is confirmed by:
- Microscopy and culture of skin scrapings
- Histopathological examination of skin or nail biopsy using periodic acid-Schiff (PAS) stains to reveal fungal elements
- Specific antigen tests using molecular biology techniques.