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Author: Dr Amy Stanway, Dermatology Registrar, Nottingham, United Kingdom, 2005.
Acquired keratoderma is a palmoplantar keratoderma that is NOT inherited as a primary genetic condition. It may occur as part of a generalised skin condition (some of which may be inherited) or as a result of another illness.
Acquired palmoplantar keratoderma is more likely to present in adulthood (compared with inherited keratodermas which usually present in childhood). It presents with thickening of the skin of the palms and/or soles which may be diffuse (involving most of the palms and soles) or focal (localised mainly to pressure areas).
Inflammatory skin conditions
Secondary to inherited conditions that may not usually result in keratoderma
Medications and toxins
The following treatments soften the thickened skin and make them less noticeable.
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