Author: Adjunct A/Prof Patrick Emanuel, Dermatopathologist, Clínica Ricardo Palma, Lima, Peru. DermNet NZ Editor in Chief: Adjunct A/Prof Amanda Oakley. October 2018.
Angiokeratoma presents as a blood-filled papule which may bleed following trauma. There are a range of clinical presentations ranging from isolated lesions of little consequence to widespread lesions associated with Fabry disease.
Histology of angiokeratoma
In angiokeratoma, the histopathology shows a vascularlesion in the superficial dermis which extends into the epidermis. There is epidermalhyperplasia and papillomatosis. There may be intravascularthrombosis (figures 1,2).