Author: Dr Ben Tallon, Dermatologist/Dermatopathologist, Tauranga, New Zealand, December 2016.
Angioleiomyoma is an uncommon smooth muscle tumour arising from the smooth muscle of the vessel wall.
Histology of angioleiomyoma
Scanning magnification view of angioleiomyoma shows a circumscribedtumournodule arising in the dermis or subcutaneous tissue (figure 1). The tumour is comprised of densely packed interlacing bundles of smooth muscle which surround small compressed vascular channels (figures 2, 3).
Myopericytoma: While this entity is also a circumscribednodule which stains positively for muscle markers, it is comprised of perivascular concentrically arranged plump spindle to oval cells (glomoid-like) with eosinophilic cytoplasm.
Weedon’s Skin Pathology (Third edition, 2010). David Weedon
Pathology of the Skin (Fourth edition, 2012). McKee PH, J. Calonje JE, Granter SR
Hachisuga T, Hashimoto H, Enjoji M: Angioleiomyoma:A clinicopathologic reappraisal of 562 cases. Cancer 1984, 54:126-130