How do you get clear cell acanthoma and who is at risk?
It is currently not known why clear cell acanthoma occur. Although rare, they occur mostly in adults of middle-age or older. Both male and females can be affected.
How is the diagnosis made?
The diagnosis is rarely made before skin biopsy. However, dermatoscopy is characteristic, as the blood vessels are lined up in strings (see images above). When examined under the microscope, clear cell acanthoma show a characteristic accumulation of clear glycogen-containing cells in the epidermis.
What treatments are available?
They may persist for years and years without changing or causing any complications. They are easily excised.
Book: Textbook of Dermatology. Ed Rook A, Wilkinson DS, Ebling FJB, Champion RH, Burton JL. Fourth edition. Blackwell Scientific Publications.