Lichen striatus pathology

Author: A/Prof Patrick Emanuel, Dermatopathologist, Auckland, New Zealand, 2013.

Lichen striatus presents as as an erythematous papules which often join together to form a linear band following Blaschko lines.

Histology of lichen striatus

In lichen striatus, sections show a lichenoid infiltrate involving an epidermis which is usually acanthotic (figure 1). The infiltrate can be very dense or quite sparse (figures 1, 2) and there may be numerous melanophages in the superficial dermis. Apoptotic keratinocytes are usually seen at all levels of the epidermis.

The infiltrate typically extends to involve eccrine structures (figure 3).

Special studies of lichen striatus

None are generally needed.

Differential diagnosis of lichen striatus

The clinical presentation is helpful.

Lichen planus or lichen planus-like keratosis – The infiltrate does not usually involved eccrine glands and apoptotic keratinocytes are mainly limited to basal epidermis rather than all levels of the epidermis.

Annular lichenoid dermatitis of youth – The histology may be identical and annular lichen striatus may actually be the same disorder.

Unilateral laterothoracic exanthem – May also exhibit eccrine infiltrates

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