Marginal keratoderma

Author: DermNet NZ Editor in Chief: Adjunct A/Professor Amanda Oakley, Dermatologist, Hamilton, New Zealand. Copy edited by Maria McGivern/Gus Mitchell. July 2018. 


What is marginal keratoderma?

Marginal keratoderma is a form of palmoplantar keratoderma in which there are small firm warty or pearly papules on the sides of the hands and, in some cases, feet. 

Marginal keratoderma

How is marginal keratoderma classified?

There are inherited and acquired forms of marginal keratoderma.

Inherited marginal keratoderma

The inherited form of marginal keratoderma is acrokeratoelastoidosis, which was first described by Costa in 1953; hence, it is sometimes called Costa acrokeratoelastoidosis. It affects both hands and feet. 

Focal acral keratosis is a variant of acrokeratoelastoidosis.

Acquired marginal keratoderma

The acquired form of marginal keratoderma is often called keratoelastoidosis marginalis and is more common than acrokeratoelastoidosis.

Keratoelastoidosis marginalis is characterised by keratotic papules on the sides of the index fingers and thumbs in patients who have had a lot of exposure to the sun. 

Other names for marginal keratoderma are degenerative collagenous plaques of the hands, marginal papular acrokeratoderma, marginal keratoelastoidosis of the hands, collagenous and elastotic marginal plaques of the hands, and digital papular calcific elastosis.  

Further information about marginal keratodermas

See the DermNet pages on Acrokeratoelastoidosis and Keratoelastoidosis marginalis.

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