Author: Assoc Prof Patrick Emanuel, Dermatopathologist, Auckland, New Zealand. January 2015.
Poststeroid panniculitis is a rare complication of systemic corticosteroid therapy. Clinically, erythematousnodules and indurated plaques develop on the cheeks of children within days or weeks following rapid systemic steroid tapering or cessation.
Histology of poststeroid panniculitis
Poststeroid panniculitis presents as lobular panniculitis with a mixed inflammatoryinfiltrates without vasculitis. Needle-shaped crystals within adipocytes are characteristic (figure 1). The clefts may be surrounded by foreign body giant cells.