Sclerema neonatorum pathology
Sclerema neonatorum usually affects gravely ill, preterm neonates in the first week of life. It is characterised by hardening of the skin that gets bound down to the underlying structures.
Histology of sclerema neonatorum
In sclerema neonatorum, needle-shaped crystals are arranged radially in adipocytes. There is little or no associated inflammatory infiltrate and no fat necrosis (figures 1, 2).
Special studies for sclerema neonatorum
None are generally needed.