Splenosis pathology

Author: Adjunct A/Prof Patrick Emanuel, Dermatopathologist, Clínica Ricardo Palma, Lima, Peru. DermNet NZ Editor in Chief: Adjunct A/Prof Amanda Oakley. Copy edited by Gus Mitchell. September 2018.


Introduction

Splenosis may present in the skin following splenic trauma and subsequent spread of benign splenic tissue into surrounding structures.

Histology of splenosis

In splenosis, the histopathology shows normal splenic tissue, usually located in the subcutis (figures 1, 2). Spleen can be recognised by the presence of red pulp (composed of venous sinusoids allowing passing of red blood cells) and white pulp (composed of sheaths of lymphoid cells around arteries).

Splenosis pathology

Special studies for splenosis

None are generally needed.

Differential diagnosis for splenosis

Other diagnoses to be considered include a dermal lymph node: this lacks the components seen in splenic tissue (red and white pulp).

Ask an online dermatologist now
Securely upload your symptoms and pictures using First Derm
(Sponsored content)

 

Related information

 

References

  • Gupta K, Ahluwalia A, Jain T, Saggar K. Abdominal splenosis mimicking peritoneal deposits- A case report. The Pan African Medical Journal 2014; 17: 269. doi:10.11604/pamj.2014.17.269.3413. PubMed Central

On DermNet NZ

Other websites

Books about skin diseases

See the DermNet NZ bookstore.