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Facts about the skin from DermNet New Zealand Trust. Topic index: A B C D E F G H I J K L M N O P Q R S T U V W X Y Z



Chronic mucocutaneous candidiasis

What is chronic mucocutaneous candidiasis?

Chronic mucocutaneous candidiasis is a rare condition occurring in childhood in which candida infection is persistent and widespread.

It may be associated with:

Rarely, chronic mucocutaneous candidiasis develops in adult life. This is often as a result of a thymoma (tumour of the thymus gland) and is associated with internal diseases such as myasthenia gravis, myositis, aplastic anaemia, neutropaenia and hypogammaglobulinaemia.

Clinical features of chronic mucocutaneous candidiasis

Chronic mucocutaneous candidiasis usually presents before the age of 3 years with one or more of the following:

Affected patients are also susceptible to infection with dermatophyte fungi (tinea) and human papilloma virus (warts).

How is chronic mucocutaneous candidiasis diagnosed?

The diagnosis of chronic mucocutaneous candidiasis, is made on clinical grounds. Microscopy and culture of skin swabs and scrapings confirm the presence of organisms.

How is chronic mucocutaneous candidiasis treated?

The underlying defect is not as yet treatable. Treatment depends on antifungal agents orally for repeated or prolonged courses often in higher doses than is normally necessary for candida infections.

Drug resistance may occur.

Related information

References:

On DermNet NZ:

Other websites:

Books about candida:

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If you have any concerns with your skin or its treatment, see a dermatologist for advice.