Author: Dr Weng Chyn Chan MB ChB, Dept of Dermatology Waikato Hospital, Hamilton, New Zealand, 2004.
Clindamycin is a lincosamide antibiotic. It is used to treat infections due to susceptible bacteria.
Clindamycin can be used topically, orally or intravenously. In New Zealand (July 2017), it is available on prescription as:
In other countries, it may also be available as a topical foam, vaginal cream and oral suspension.
Clindamycin is quickly absorbed after oral administration and absorption is not affected by food.
Clindamycin is prescribed by dermatologists for a variety of skin conditions.
Indications for clindamycin solution, gel or lotion include:
Clindamycin is also available to treat acne in combination with benzyol peroxide, e.g. Duac® Once Daily gel.
Clindamycin vaginal cream is used to treat bacterial vaginosis.
Together with rifampicin, uses for oral clindamycin include:
Clindamycin is active against gram positive organisms (Staphylococcus aureus, Staphylococcus epidermidis, streptococci and proprionibacterium) and gram negative organisms (bacteroides species). Susceptible organisms include both aerobic and anaerobic bacteria.
Oral clindamycin is generally well tolerated. However there are important side effects that may affect some people taking the medicine orally or by injection (they are very rarely seen with the topical preparations).
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