Drug-induced nummular dermatitis

Author: Brian Wu, MD candidate, Keck School of Medicine, Los Angeles, USA. DermNet New Zealand Editor in Chief: Hon A/Prof Amanda Oakley, Dermatologist, Hamilton, New Zealand. Copy editor: Maria McGivern. June 2017.

What is nummular dermatitis?

Nummular dermatitis is a common inflammatory disorder of the skin. It is also known as nummular eczema, discoid eczema or discoid dermatitis due to its distinctive, disc-shaped lesions. It can also be referred to as exudative neurodermatitis or nummular eczematous dermatitis

What is drug-induced nummular dermatitis?

The drug-induced form of nummular dermatitis is diagnosed when its onset is associated with certain medications.

Who gets drug-induced nummular dermatitis?

Drug-induced nummular dermatitis has similar risk factors to the non-drug-induced form of nummular dermatitis; these include:

What causes drug-induced nummular dermatitis?

Nummular dermatitis can be caused by drugs that affect the function of the epidermal barrier or immune response. Drugs that can lead to excessive skin dryness and dermatitis include:

What are the clinical symptoms of nummular dermatitis?

Nummular dermatitis presents with bilateral, well-defined circular, oval or disc-shaped erythematous plaques. They can be dry or exudative (oozy).

How is drug-induced nummular dermatitis diagnosed?

The diagnosis of drug-induced nummular dermatitis is based on taking a careful patient history and a physical examination. Additional investigations may include:

How is drug-induced nummular dermatitis treated?

Treatments for nummular dermatitis aim to rehydrate the skin and repair the epidermal barrier. Treatment can include:

What is the outcome for drug-induced nummular dermatitis?

Nummular dermatitis may take months or sometimes years to resolve. When drug-induced, it may clear up more quickly on the cessation of the medicine that caused the dermatitis to appear.

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