DermNet provides Google Translate, a free machine translation service. Note that this may not provide an exact translation in all languages
Author: Assoc Prof Patrick Emanuel, Dermatopathologist, Auckland, New Zealand, 2013.
The hibernoma is derived from brown fat. They occur in the subcutaneous or deeper soft tissues.
Sections show a highly characteristic lesion composed of cells with a markedly enlarged cytoplasm filled with course vacuoles and eosinophilic granules (figures 1, 2).
None are generally needed. Cytogenetic studies of hibernoma have shown deletions on chromosomes 10 and 11 but are not required for diagnosis.
Normal brown fat — Brown fat may be seen incidentally in paediatric soft tissues. Physiologic brown fat does not form a discrete mass.
Granular cell tumour, rhabdomyomas — These tumours contain eosinophilic granules in the cytoplasm. Intracytoplasmic vacuoles are not seen in these tumours.
© 2021 DermNet New Zealand Trust.
DermNet NZ does not provide an online consultation service. If you have any concerns with your skin or its treatment, see a dermatologist for advice.