Author: Hon A/Prof Amanda Oakley, Dermatologist, Hamilton, New Zealand, September 2015.
What are neutrophilicdermatoses?
Neutrophilic dermatoses are autoinflammatory skin conditions characterised by dense infiltration of inflammatory cells (neutrophils) in the affected tissue. They arise in reaction to some underlying systemic illness. A neutrophilic dermatosis may be seen in isolation or more than one type may occur in the same individual.
Neutrophilic dermatoses often arise at the site of injury such as a needle prick, biopsy or insect bite. This reaction to injury is known as Koebner phenomenon, or isomorphic response. Pathergy refers to papules and pustules appearing at the site of needle stick.