Author: Dr Amanda Oakley, Dermatologist, Hamilton, New Zealand, 1997. Updated September 2015.
A blistering disease is a condition in which there are fluid-filled skin lesions.
Acute blistering diseases can be generalised or localised to one body site and are due to infection or inflammatory disorders. Although most commonly eczematous, generalised acute blistering diseases can be life-threatening and often necessitate hospitalisation.
Atypical enterovirus infection
Enteroviral vesicular stomatitis
Clears in a few days
Diagnosis of chronic blistering diseases often requires skin biopsy for histopathology and direct immunofluorescence. A blood test for specific antibodies (indirect immunofluorescence) may also prove helpful in making the diagnosis of an immunobullous disease.
Other immunobullous diseases
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