Author: Vanessa Ngan, Staff Writer, 2002.
Cobalt is a metal found naturally in soil, dust, and seawater. It is usually found in association with nickel. Cobalt and its salts have many uses, the table below shows some of the many sources of cobalt and where or how we may come into contact with them either at home or at work.
Reactions to contact with cobalt in an allergic individual include allergic contact dermatitis and irritant contact dermatitis. Cobalt was named Contact Allergen of the Year 20162 by the American Contact Dermatitis Society.
Vitamin B12 injections administered to allergic individuals may produce a red, tender and itchy area around the site of the injection. Oral ingestion of vitamin B12 is known to cause intractable hand eczema is some patients.
In many cases, allergic reactions are not caused solely by cobalt sensitisation. For example, metal objects almost always also contain nickel and in the cement industry nickel and chromium are present. Nickel and chromium are also potent sensitisers therefore; allergic reactions may not be due solely to cobalt but also to simultaneous specific allergy to nickel and chromium.
Cobalt allergy may cause an erythema multiforme-like eruption. It may also cause an airborne contact dermatitis.
Cobalt allergy is diagnosed from the clinical history and by performing patch tests.
Nickel and cobalt are always found together in alloys and salts because it is too costly and impracticable to separate these two metals. Thus patch testing should always include both cobalt and nickel. Patch test results with cobalt and nickel can be confusing as it is extremely difficult to obtain pure solutions of each individual metal. Cross-reaction between cobalt and nickel is not very frequent, as patch tests have shown several patients with strong reactions to cobalt but not to nickel. Combined allergic reactions are not uncommon and represent simultaneous specific sensitisations to each individual metal as opposed to being cross-reactions. Intradermal testing with cobalt may also be performed to diagnose cobalt sensitivity. Current thinking is that a diagnosis of allergic dermatitis to cobalt is justified if the following criteria are matched.
Confirmed diagnosis of allergic cobalt dermatitis
Identifying possible sources of contact and avoiding them is the only long-term management strategy for cobalt allergy. Once the dermatitis appears on the skin, treatment is as for any acute dermatitis/eczema:
Where avoidance is not achievable, several methods can be used to try to minimise exposure. Brief contact with metal devices is usually not a problem except in highly sensitive individuals.
Methods to minimise cobalt exposure
In the workplace try to avoid exposure to cobalt, however this may not be practicable thus use measures to minimize exposure as described above. Identify potential sources of exposure using Material Safety Data Sheets; these are required for all chemicals and substances that you may come into contact with in the workplace. If you must use products that contain cobalt, wear gloves or other protective clothing to avoid contact with your skin.
Outside of the workplace, the best way to avoid cobalt allergy is by being aware of the possible sources of cobalt. Read product labels and do not use any that contain cobalt or any of its alternative names. If unsure ask your pharmacist for advice or a suitable alternative. Only use cosmetics, antiperspirants and hair dyes that you know do not contain cobalt. Avoid metallic costume jewellery. Sterling silver and platinum jewellery is usually tolerated.
A cobalt allergy spot test kit containing disodium-1-nitroso-2-naphthol-3,6-disulfonate (nitroso R salt) is available from contact allergen supply companies and can be used to detect cobalt in metal items such as jewellery.
Alert your doctor or dentist to the fact that you have an allergy to cobalt. Your dermatologist may have further specific advice, particularly if you are highly sensitive to cobalt.
Cobalt is also known by several other names. These include:
Avoid all of these. At work, request a material safety data sheet to help identify alternatives that are safe hence avoiding contact with material containing cobalt.
CAS number: 7791-13-1
Appearance: Silvery grey, shiny, hard metal
Sources of Exposure to Cobalt
Thyssen JP, Menné T, Johansen JD, Lidén C, Julander A, Møller P, Jellesen MS. A spot test for detection of cobalt release - early experience and findings. Contact Dermatitis. 2010 Aug;63(2):63-9. doi: 10.1111/j.1600-0536.2010.01749.x. Epub 2010 Jun 18. PubMed PMID: 20573165. PubMed.
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